SCHEMBL23958756

SCHEMBL23958756

Cc1c(C(CNC=O)C2CC2)nc(-c2ccc(F)cc2)c(F)c1C(C)(C)O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 3/20 0.33
ACACB O00763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23958860 0.75 RPS6KB1 (0.33) SLC34A1
SCHEMBL23958587 0.74 CFTR (0.34)
SCHEMBL23958739 0.72 TRPV3 (0.34) SLC34A1
SCHEMBL25686856 0.67 SLC34A1 (0.34) SLC34A1
SCHEMBL30007397 0.67 SLC34A1 (0.34) SLC34A1
SCHEMBL23958793 0.67 CFTR (0.35) SLC34A1
SCHEMBL25234571 0.67 CKS1B (0.35) SLC34A1
SCHEMBL30007134 0.67 SLC34A1 (0.36) SLC34A1
SCHEMBL25686851 0.67 SLC34A1 (0.36) SLC34A1
SCHEMBL30006977 0.66 SLC34A1 (0.35) SLC34A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021214136-A1 RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES Janssen Sciences Ireland Unlimited Company (IE) 2021-10-28 WO disclosed