Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3427967 | 0.93 | PARP1 (0.47) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3427703 | 0.93 | PARP1 (0.47) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4414124 | 0.92 | PARP1 (0.46) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29908356 | 0.92 | PARP1 (0.46) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5083476 | 0.89 | OPRL1 (0.46) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3955549 | 0.86 | PARP1 (0.52) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28284464 | 0.86 | PIK3C3 (0.44) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29373648 | 0.85 | ALDH1A1 (0.42) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29687939 | 0.85 | PARP1 (0.46) | PARP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1116651 | 0.85 | PARP1 (0.46) | PARP1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654130-A | Use of a composition for enhancing night repair related functions of skin | 联合利华知识产权控股有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-117915890-A | Deodorant composition | 联合利华知识产权控股有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-111787903-B | Disinfectant composition | 联合利华知识产权控股有限公司 | 2023-08-15 | — | — | CN | claimed |
| EP-3764975-B1 | A SANITIZER COMPOSITION | UNILEVER GLOBAL IP LTD (GB) | 2021-10-13 | — | — | EP | claimed |
| CN-111787903-A | Disinfectant composition | 荷兰联合利华有限公司 | 2020-10-16 | — | — | CN | claimed |
| CN-103958478-B | Bicyclic dihydroisoquinolin-1-one derivatives | 霍夫曼-拉罗奇有限公司 | 2017-08-01 | — | — | CN | claimed |
| WO-2006068410-A1 | NOVEL 3-(2-AMINO-6-PYRIDINYL)-4-HYDROXYPHENYL AMINE DERIVATIVES | LG LIFE SCIENCES, LTD. (KR) | 2006-06-29 | — | — | WO | claimed |
| CN-119654130-A | Use of a composition for enhancing night repair related functions of skin | 联合利华知识产权控股有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-117915890-A | Deodorant composition | 联合利华知识产权控股有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-111787903-B | Disinfectant composition | 联合利华知识产权控股有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-111787903-A | Disinfectant composition | 荷兰联合利华有限公司 | 2020-10-16 | — | — | CN | disclosed |
| CN-103958478-B | Bicyclic dihydroisoquinolin-1-one derivatives | 霍夫曼-拉罗奇有限公司 | 2017-08-01 | — | — | CN | disclosed |
| US-9428456-B2 | 1-[m-carboxamido(hetero)aryl-methyl]-heterocyclyl-carboxamide derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2016-08-30 | — | — | US | disclosed |
| US-7514456-B2 | Nicotinamide derivatives useful as p38 inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-07 | — | — | US | disclosed |
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRUENENTHAL GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
| US-20060281763-A1 | Carboxamide inhibitors of TGFbeta | SCIOS INC. | 2006-12-14 | — | — | US | disclosed |
| US-20060276516-A1 | Nicotinamide Derivatives Useful as p38 Inhibitors | SMITHKLINE BEECHAM CORPORATION | 2006-12-07 | — | — | US | disclosed |
| US-20060264479-A1 | Nicotinamide Derivatives Useful as p38 Inhibitors | SMITHKLINE BEECHAM CORPORATION | 2006-11-23 | — | — | US | disclosed |
| US-7125898-B2 | Nicotinamide derivatives useful as p38 inhibitors. | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-24 | — | — | US | disclosed |
| US-20050176964-A1 | Nicotinamide derivatives useful as p38 inhibitors | GLAXOSMITHKLINE LLC | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264479-A1 | Nicotinamide Derivatives Useful as p38 Inhibitors | MAPK1, MAPK7, MAPK6 | PARP1 1139/4885KDM4E 4790/4885ALDH1A1 723/4885 |
| US-20060281763-A1 | Carboxamide inhibitors of TGFbeta | TGFBR1, TGFBR2, TGFB1 | PARP1 873/4885KDM4E 229/4885ALDH1A1 1830/4885 |
| US-20060276516-A1 | Nicotinamide Derivatives Useful as p38 Inhibitors | MAPK1, MAPK7, MAPK6 | PARP1 1139/4885KDM4E 4790/4885ALDH1A1 723/4885 |
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRM1, GRIN1, GRM2 | PARP1 4537/4885KDM4E 2026/4885ALDH1A1 2269/4885 |
| US-20050176964-A1 | Nicotinamide derivatives useful as p38 inhibitors | MAPK1, MAPK7, MAPK6 | PARP1 1139/4885KDM4E 4790/4885ALDH1A1 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.