SCHEMBL23960608

SCHEMBL23960608

CC(C)(C)OC(=O)NCc1cccc(OC2CNCC(c3ccccc3F)C2)c1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 3/20 0.39
CREBBP Q92793 1/20 0.39
GLS O94925 4/20 0.36
S1PR3 Q99500 2/20 0.36
NAMPT P43490 1/20 0.36
ROCK2 O75116 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CACNA1B Q00975 1/20 0.35
KDM4A O75164 1/20 0.35
HRH1 P35367 1/20 0.35
GFER P55789 1/20 0.35
HSD17B10 Q99714 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HDAC4 P56524 1/20 0.35
EP300 Q09472 1/20 0.35
MEF2D Q14814 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30151671 1.00 BRD4 (0.39) BRD4CREBBPGLSS1PR3NAMPT
SCHEMBL23932342 0.88 HRH1 (0.41) S1PR3KDM4EALDH1A1HRH1HSD17B10
SCHEMBL26078682 0.87 BRD4 (0.41) BRD4CREBBPGLSNAMPTROCK2
SCHEMBL30151669 0.87 BRD4 (0.41) BRD4CREBBPGLSNAMPTROCK2
SCHEMBL23960541 0.76 NAMPT (0.44) NAMPTHSD17B10L3MBTL1
SCHEMBL23932334 0.74 HRH1 (0.44) HRH1HSD17B10
SCHEMBL3418637 0.70 ALDH1A1 (0.62) KDM4EALDH1A1GFERHSD17B10L3MBTL1
SCHEMBL52448 0.70 GRM2 (0.44) BRD4CREBBPGLSNAMPTKDM4A
SCHEMBL970934 0.70 ALDH1A1 (0.42) BRD4CREBBPNAMPTALDH1A1L3MBTL1
SCHEMBL18526150 0.69 MAPK14 (0.58) GLSNAMPTROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. 2023-10-05 US disclosed
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. 2023-10-05 US disclosed
WO-2021216592-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS LOX, LOXL1, LOXL2 BRD4 988/4885CREBBP 1574/4885GLS 499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.