SCHEMBL23960643

SCHEMBL23960643

CC(C)(C)OC(=O)NCc1cccc(O[C@@H]2C[C@H](c3ccccc3)CN(C(=O)N3CCOCC3)C2)c1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F2R P25116 5/20 0.52
DGAT2 Q96PD7 1/20 0.39
KIF11 P52732 1/20 0.39
S1PR3 Q99500 1/20 0.38
TACR1 P25103 3/20 0.38
ROCK2 O75116 1/20 0.37
MGLL Q99685 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30151697 1.00 F2R (0.52) F2RDGAT2KIF11S1PR3TACR1
SCHEMBL30636560 1.00 F2R (0.52) F2RDGAT2KIF11S1PR3TACR1
SCHEMBL23932346 0.90 F2R (0.54) F2RDGAT2KIF11TACR1MGLL
SCHEMBL30151696 0.83 F2R (0.53) F2RDGAT2KIF11TACR1MGLL
SCHEMBL23960644 0.83 F2R (0.53) F2RDGAT2KIF11TACR1MGLL
SCHEMBL30151669 0.79 BRD4 (0.41) ROCK2
SCHEMBL26078682 0.79 BRD4 (0.41) ROCK2
SCHEMBL23960534 0.72 F2R (0.43) F2R
SCHEMBL23960590 0.72 F2R (0.43) F2R
SCHEMBL23932436 0.72 F2R (0.43) F2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. 2023-10-05 US disclosed
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. 2023-10-05 US disclosed
WO-2021216592-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS LOX, LOXL1, LOXL2 F2R 300/4885DGAT2 572/4885KIF11 4736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.