SCHEMBL23960644

SCHEMBL23960644

NCc1cccc(O[C@@H]2C[C@H](c3ccccc3)CN(C(=O)N3CCOCC3)C2)c1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
F2R P25116 4/20 0.53
MGLL Q99685 1/20 0.42
ALDH1A1 P00352 1/20 0.41
KIF11 P52732 1/20 0.40
TACR1 P25103 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
OPRK1 P41145 1/20 0.38
SCD O00767 1/20 0.38
SCD5 Q86SK9 1/20 0.38
EPHX1 P07099 1/20 0.38
HSD17B10 Q99714 1/20 0.38
AKR1C3 P42330 2/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
DGAT2 Q96PD7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30151696 1.00 F2R (0.53) F2RMGLLALDH1A1KIF11TACR1
SCHEMBL23932346 0.89 F2R (0.54) F2RMGLLALDH1A1KIF11TACR1
SCHEMBL23932436 0.88 F2R (0.43) F2RALDH1A1HRH3OPRK1KMT2A
SCHEMBL30151661 0.88 F2R (0.43) F2RALDH1A1HRH3OPRK1KMT2A
SCHEMBL23960590 0.88 F2R (0.43) F2RALDH1A1HRH3OPRK1KMT2A
SCHEMBL23960534 0.88 F2R (0.43) F2RALDH1A1HRH3OPRK1KMT2A
SCHEMBL30636560 0.83 F2R (0.52) F2RMGLLKIF11TACR1DGAT2
SCHEMBL30151697 0.83 F2R (0.52) F2RMGLLKIF11TACR1DGAT2
SCHEMBL23960643 0.83 F2R (0.52) F2RMGLLKIF11TACR1DGAT2
SCHEMBL23932369 0.74 RORC (0.37) OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. 2023-10-05 US disclosed
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. 2023-10-05 US disclosed
WO-2021216592-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS ANOVIA BIOSCIENCES, INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310445-A1 LOX ENZYME INHIBITING METHODS AND COMPOSITIONS LOX, LOXL1, LOXL2 F2R 300/4885MGLL 48/4885ALDH1A1 487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.