SCHEMBL23960812

SCHEMBL23960812

CC1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.75

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ FBP1 P09467 2/20 0.75
▸ AMDHD2 Q9Y303 1/20 0.56
▸ IGF2R P11717 4/20 0.53
▸ P2RY2 P41231 2/20 0.43
▸ P2RY6 Q15077 1/20 0.43
▸ UMPS P11172 3/20 0.42
▸ ATIC P31939 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15765675 1.00 FBP1 (0.75) FBP1AMDHD2IGF2RP2RY2P2RY6
SCHEMBL14503325 1.00 FBP1 (0.75) FBP1AMDHD2IGF2RP2RY2P2RY6
SCHEMBL14985153 1.00 FBP1 (0.75) FBP1AMDHD2IGF2RP2RY2P2RY6
SCHEMBL18294135 1.00 FBP1 (0.75) FBP1AMDHD2IGF2RP2RY2P2RY6
SCHEMBL10064521 1.00 FBP1 (0.75) FBP1AMDHD2IGF2RP2RY2P2RY6
SCHEMBL19454793 1.00 FBP1 (0.75) FBP1AMDHD2IGF2RP2RY2P2RY6
SCHEMBL13857406 0.98 FBP1 (0.72) FBP1AMDHD2IGF2RP2RY2P2RY6
SCHEMBL29323929 0.98 FBP1 (0.72) FBP1AMDHD2IGF2RP2RY2P2RY6
SCHEMBL18710783 0.98 FBP1 (0.72) FBP1AMDHD2IGF2RP2RY2P2RY6
SCHEMBL29324521 0.98 FBP1 (0.72) FBP1AMDHD2IGF2RP2RY2P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321131-A1 NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT AND PREVENTION OF AN ANTINEOPLASTIC-INDUCED TOXICITY NUVAMID SA (CH) 2023-10-12 — — US disclosed
US-11730752-B2 Use of NMN for the prevention and/or treatment of joint pain induced by physical activity, and corresponding compositions NUVAMID SA (CH) 2023-08-22 — — US disclosed
US-20230210881-A1 NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS NUVAMID SA (CH) 2023-07-06 — — US disclosed
US-20230210746-A1 ANTI-AGING COSMETIC COMPOSITIONS COMPRISING NMN NUVAMID SA (CH) 2023-07-06 — — US disclosed
US-20230172959-A1 USE OF NMN FOR THE PREVENTION AND/OR TREATMENT OF A BACK PAIN AND CORRESPONDING COMPOSITIONS NUVAMID SA (CH) 2023-06-08 — — US disclosed
US-20230150984-A1 NICOTINAMIDE MONONUCLEOTIDE AND NICOTINAMIDE RIBOSIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF VIRAL INFECTIONS AND RESPIRATORY COMPLICATIONS, IN PARTICULAR CAUSED BY INFLUENZAVIRUS OR CORONAVIRUS NUVAMID SA (CH) 2023-05-18 — — US disclosed
US-20230136569-A1 USE OF NMN TO REDUCE IMMUNODEPRESSION AND IMMUNOSENESCENCE NUVAMID SA (CH) 2023-05-04 — — US disclosed
US-20230096443-A1 NOVEL NICOTINAMIDE DI-NUCLEOTIDE DERIVATIVES AND USE THEREOF NUVAMID SA (CH) 2023-03-30 — — US disclosed
US-20230060438-A1 USE OF NMN FOR THE PREVENTION AND/OR TREATMENT OF JOINT PAIN INDUCED BY PHYSICAL ACTIVITY, AND CORRESPONDING COMPOSITIONS NUVAMID SA (CH) 2023-03-02 — — US disclosed
US-20210353656-A1 COMBINATION OF NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND HISTAMINE H2 RECEPTOR ANTAGONISTS FOR VIRAL INFECTIONS NUVAMID SA (CH) 2021-11-18 — — US disclosed
US-20210332033-A1 NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF VIRAL INFECTIONS NUVAMID SA (CH) 2021-10-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172959-A1 USE OF NMN FOR THE PREVENTION AND/OR TREATMENT OF A BACK PAIN AND CORRESPONDING COMPOSITIONS NNT, NAMPT, UTRN FBP1 334/4885AMDHD2 517/4885IGF2R 3637/4885
US-20230150984-A1 NICOTINAMIDE MONONUCLEOTIDE AND NICOTINAMIDE RIBOSIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF VIRAL INFECTIONS AND RESPIRATORY COMPLICATIONS, IN PARTICULAR CAUSED BY INFLUENZAVIRUS OR CORONAVIRUS NAMPT, NNT, NADK FBP1 154/4885AMDHD2 101/4885IGF2R 1773/4885
US-20230060438-A1 USE OF NMN FOR THE PREVENTION AND/OR TREATMENT OF JOINT PAIN INDUCED BY PHYSICAL ACTIVITY, AND CORRESPONDING COMPOSITIONS NNT, NAMPT, NMUR1 FBP1 1061/4885AMDHD2 261/4885IGF2R 3352/4885
US-20210353656-A1 COMBINATION OF NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND HISTAMINE H2 RECEPTOR ANTAGONISTS FOR VIRAL INFECTIONS HRH2, HRH4, HRH3 FBP1 470/4885AMDHD2 186/4885IGF2R 583/4885
US-20230210881-A1 NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS NNT, NAMPT, ME1 FBP1 118/4885AMDHD2 155/4885IGF2R 1207/4885
US-20230321131-A1 NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT AND PREVENTION OF AN ANTINEOPLASTIC-INDUCED TOXICITY NAMPT, NNT, NQO1 FBP1 375/4885AMDHD2 122/4885IGF2R 2893/4885
US-11730752-B2 Use of NMN for the prevention and/or treatment of joint pain induced by physical activity, and corresponding compositions NNT, NAMPT, NMUR1 FBP1 1061/4885AMDHD2 261/4885IGF2R 3352/4885
US-20230210746-A1 ANTI-AGING COSMETIC COMPOSITIONS COMPRISING NMN NCL, POLN, CUTA FBP1 3695/4885AMDHD2 102/4885IGF2R 4504/4885
US-20230136569-A1 USE OF NMN TO REDUCE IMMUNODEPRESSION AND IMMUNOSENESCENCE NAMPT, NNT, NNMT FBP1 1251/4885AMDHD2 67/4885IGF2R 1681/4885
US-20230096443-A1 NOVEL NICOTINAMIDE DI-NUCLEOTIDE DERIVATIVES AND USE THEREOF NNT, NAMPT, NQO1 FBP1 1241/4885AMDHD2 411/4885IGF2R 4537/4885
US-20210332033-A1 NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF VIRAL INFECTIONS NAMPT, NNT, NNMT FBP1 200/4885AMDHD2 87/4885IGF2R 1810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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