SCHEMBL23960933

SCHEMBL23960933

c1ccc(-c2nc3ccc4ccc5ccc(-c6nc(-c7ccc8ccccc8c7)nc(-c7ccc8ccccc8c7)n6)cc5c4c3o2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.44
ALDH1A1 P00352 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
TP53 P04637 2/20 0.42
CYP1A2 P05177 2/20 0.42
HSD17B10 Q99714 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 4/20 0.40
ELANE P08246 1/20 0.40
ESR2 Q92731 3/20 0.40
ESR1 P03372 2/20 0.40
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38
NPC1 O15118 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23511824 0.99 ALDH1A1 (0.44) DHODHALDH1A1SMN1; SMN2TP53CYP1A2
SCHEMBL24372612 0.94 DHODH (0.43) DHODHALDH1A1SMN1; SMN2TP53CYP1A2
SCHEMBL20391608 0.94 DHODH (0.47) DHODHALDH1A1SMN1; SMN2KDM4EMEN1
SCHEMBL21661851 0.94 DHODH (0.47) DHODHALDH1A1SMN1; SMN2TP53CYP1A2
SCHEMBL20391874 0.94 DHODH (0.47) DHODHALDH1A1SMN1; SMN2KDM4EMEN1
SCHEMBL21662023 0.94 DHODH (0.47) DHODHALDH1A1SMN1; SMN2TP53CYP1A2
SCHEMBL23511827 0.94 DHODH (0.47) DHODHALDH1A1SMN1; SMN2KDM4EMEN1
SCHEMBL21158031 0.93 DHODH (0.44) DHODHALDH1A1SMN1; SMN2TP53CYP1A2
SCHEMBL23600078 0.91 SMN1; SMN2 (0.44) DHODHALDH1A1SMN1; SMN2TP53CYP1A2
SCHEMBL21000754 0.91 SMN1; SMN2 (0.44) DHODHALDH1A1SMN1; SMN2TP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220356193-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-11-10 US disclosed
US-20220131083-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-04-28 US disclosed
US-20210336153-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356193-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PIEZO1, SOD1, NECTIN4 DHODH 1495/4885ALDH1A1 533/4885SMN1; SMN2 1333/4885
US-20220131083-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, TERT, LIMS1 DHODH 2605/4885ALDH1A1 275/4885SMN1; SMN2 234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.