Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 2/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2396340 | 1.00 | SLC6A4 (0.51) | SLC6A4L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL31351884 | 0.88 | ALOX15 (0.50) | SLC6A4KMT2AMEN1GAACYP26A1 | |
| SCHEMBL15164584 | 0.80 | ALDH1A1 (0.47) | KMT2AGAASMN1; SMN2CYP26A1ALDH1A1 | |
| SCHEMBL2396180 | 0.79 | FFAR1 (0.48) | L3MBTL1KMT2AMEN1MRGPRX4SMN1; SMN2 | |
| SCHEMBL2396179 | 0.79 | FFAR1 (0.48) | L3MBTL1KMT2AMEN1MRGPRX4SMN1; SMN2 | |
| SCHEMBL2395015 | 0.78 | L3MBTL1 (0.56) | SLC6A4L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL2395009 | 0.78 | L3MBTL1 (0.56) | SLC6A4L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL20491186 | 0.77 | GAA (0.50) | L3MBTL1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL2394601 | 0.76 | GAA (0.61) | SLC6A4L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL2394607 | 0.76 | GAA (0.61) | SLC6A4L3MBTL1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012901-B1 | Method of synthesizing enantiopure mexiletine analogues and novel β-thiophenoxy and pyridyl ethers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-09-06 | — | — | US | disclosed |