Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 5/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25200874 | 0.78 | SIRT1 (0.52) | SIRT1DRD3DRD2DRD4LOXL2 | |
| SCHEMBL6381282 | 0.77 | HRH4 (0.68) | SIRT1DRD3DRD2DRD4LOXL2 | |
| SCHEMBL23932528 | 0.74 | KMT2A (0.52) | SIRT1DRD3DRD2DRD4CHEK1 | |
| SCHEMBL30040747 | 0.73 | DRD3 (0.56) | SIRT1DRD3DRD2DRD4LOXL2 | |
| SCHEMBL25505958 | 0.73 | DRD3 (0.56) | SIRT1DRD3DRD2DRD4LOXL2 | |
| SCHEMBL23964261 | 0.69 | DRD4 (0.64) | SIRT1DRD3DRD2DRD4LOXL2 | |
| SCHEMBL5796117 | 0.68 | CHEK1 (0.58) | CHEK1HRH4KMT2AMEN1HRH3 | |
| SCHEMBL4392078 | 0.68 | F10 (0.66) | SIRT1DRD3DRD2DRD4LOXL2 | |
| SCHEMBL30041947 | 0.67 | DRD2 (0.49) | DRD3DRD2DRD4LOXL2HRH4 | |
| SCHEMBL23932545 | 0.67 | DRD2 (0.49) | DRD3DRD2DRD4LOXL2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216665-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2021-10-28 | — | — | WO | disclosed |