Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25183371 | 0.83 | HRH4 (0.66) | DRD3DRD2DRD4HRH4HRH3 | |
| SCHEMBL23932528 | 0.83 | KMT2A (0.52) | SIRT1DRD3DRD2DRD4KMT2A | |
| SCHEMBL6381282 | 0.81 | HRH4 (0.68) | SIRT1DRD3DRD2DRD4HRH4 | |
| SCHEMBL30040747 | 0.80 | DRD3 (0.56) | SIRT1DRD3DRD2DRD4HRH4 | |
| SCHEMBL25505958 | 0.80 | DRD3 (0.56) | SIRT1DRD3DRD2DRD4HRH4 | |
| SCHEMBL23964156 | 0.78 | SIRT1 (0.45) | SIRT1DRD3DRD2DRD4KMT2A | |
| SCHEMBL4392078 | 0.76 | F10 (0.66) | SIRT1DRD3DRD2DRD4LOXL2 | |
| SCHEMBL25180592 | 0.75 | LMNA (0.56) | DRD2DRD4HRH4HRH3SMN1; SMN2 | |
| SCHEMBL23964261 | 0.75 | DRD4 (0.64) | SIRT1DRD3DRD2DRD4HRH4 | |
| Formic Acid SCHEMBL25187757 | 0.75 | DRD4 (0.57) | SIRT1DRD3DRD2DRD4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150980-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150980-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | COL1A1, COL2A1, COL14A1 | SIRT1 1534/4885DRD3 4747/4885DRD2 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.