Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.62 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.56 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23964235 | 0.86 | RPS6KB1 (0.58) | RPS6KB1HRH4KCNH2PIK3CDPIK3CB | |
| SCHEMBL30041229 | 0.86 | RPS6KB1 (0.58) | RPS6KB1HRH4KCNH2PIK3CDPIK3CB | |
| Hydrochloric Acid SCHEMBL30040164 | 0.85 | RPS6KB1 (0.57) | RPS6KB1HRH4KCNH2PIK3CDPIK3CB | |
| SCHEMBL23964164 | 0.83 | DRD4 (0.68) | RPS6KB1KCNH2DGAT1SOAT1IDO1 | |
| SCHEMBL23964138 | 0.82 | SLC2A1 (0.62) | RPS6KB1KCNH2DGAT1SOAT1PIK3CD | |
| SCHEMBL23932558 | 0.81 | RPS6KB1 (0.55) | RPS6KB1HRH4KCNH2CACNA1GCACNA1B | |
| SCHEMBL30042095 | 0.80 | RPS6KB1 (0.69) | RPS6KB1PIK3CDPIK3CBDRD4GRM2 | |
| SCHEMBL23964274 | 0.80 | RPS6KB1 (0.69) | RPS6KB1PIK3CDPIK3CBDRD4GRM2 | |
| SCHEMBL23932547 | 0.79 | RPS6KB1 (0.66) | RPS6KB1KCNH2DGAT1SOAT1PIK3CD | |
| SCHEMBL14046586 | 0.78 | DGAT1 (0.65) | HRH4KCNH2DGAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216665-A9 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2021-12-02 | — | — | WO | disclosed |
| WO-2021216665-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2021-10-28 | — | — | WO | disclosed |