SCHEMBL23964138

SCHEMBL23964138

FC(F)(F)c1ccc2nc(CN3CCN(c4ccncc4)CC3)[nH]c2c1

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 2/20 0.62
RPS6KB1 P23443 1/20 0.62
DRD4 P21917 9/20 0.54
DGAT1 O75907 1/20 0.51
SOAT1 P35610 1/20 0.51
KCNH2 Q12809 1/20 0.51
NPC1 O15118 1/20 0.50
GAA P10253 1/20 0.50
PIK3CD O00329 1/20 0.49
PIK3CB P42338 1/20 0.49
HTR1A P08908 1/20 0.47
ADRA2C P18825 1/20 0.47
HTR2A P28223 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23964164 0.90 DRD4 (0.68) SLC2A1RPS6KB1DRD4DGAT1SOAT1
SCHEMBL23932547 0.85 RPS6KB1 (0.66) SLC2A1RPS6KB1DRD4DGAT1SOAT1
SCHEMBL23964186 0.82 RPS6KB1 (0.62) RPS6KB1DRD4DGAT1SOAT1KCNH2
SCHEMBL30041229 0.81 RPS6KB1 (0.58) RPS6KB1DRD4KCNH2PIK3CDPIK3CB
SCHEMBL23964235 0.81 RPS6KB1 (0.58) RPS6KB1DRD4KCNH2PIK3CDPIK3CB
SCHEMBL30040795 0.81 SLC2A1 (0.56) SLC2A1RPS6KB1DRD4DGAT1SOAT1
SCHEMBL23964281 0.81 SLC2A1 (0.56) SLC2A1RPS6KB1DRD4DGAT1SOAT1
Hydrochloric Acid SCHEMBL30040164 0.80 RPS6KB1 (0.57) RPS6KB1DRD4KCNH2PIK3CDPIK3CB
SCHEMBL23964171 0.80 DRD4 (0.82) DRD4NPC1GAAHTR1AADRA2C
SCHEMBL23964157 0.79 SLC2A1 (0.54) SLC2A1RPS6KB1DRD4HTR1AADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
EP-4139291-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-03-01 EP disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 SLC2A1 3090/4885RPS6KB1 316/4885DRD4 4746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.