SCHEMBL23964235

SCHEMBL23964235

FC(F)(F)c1ccc2nc(CN3CCNCC3)[nH]c2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RPS6KB1 P23443 1/20 0.58
PIK3CD O00329 1/20 0.49
PIK3CB P42338 1/20 0.49
IDO1 P14902 1/20 0.49
KDM4E B2RXH2 2/20 0.48
MAPT P10636 1/20 0.48
PDE10A Q9Y233 1/20 0.47
HPGD P15428 3/20 0.46
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CACNA1G O43497 1/20 0.46
CACNA1B Q00975 1/20 0.46
KCNH2 Q12809 1/20 0.46
ATM Q13315 1/20 0.46
HTT P42858 1/20 0.46
BRS3 P32247 1/20 0.45
NPBWR1 P48145 1/20 0.45
DRD4 P21917 1/20 0.45
HRH4 Q9H3N8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30041229 1.00 RPS6KB1 (0.58) RPS6KB1PIK3CDPIK3CBIDO1KDM4E
Hydrochloric Acid SCHEMBL30040164 0.99 RPS6KB1 (0.57) RPS6KB1PIK3CDPIK3CBIDO1KDM4E
SCHEMBL23964186 0.86 RPS6KB1 (0.62) RPS6KB1PIK3CDPIK3CBIDO1KDM4E
SCHEMBL23964164 0.82 DRD4 (0.68) RPS6KB1IDO1KCNH2DRD4
SCHEMBL23964138 0.81 SLC2A1 (0.62) RPS6KB1PIK3CDPIK3CBKCNH2DRD4
SCHEMBL23964352 0.80 TDP1 (0.56) KDM4EMAPTHPGDALDH1A1HSD17B10
SCHEMBL23932547 0.78 RPS6KB1 (0.66) RPS6KB1PIK3CDPIK3CBKDM4EALDH1A1
SCHEMBL2418843 0.77 HTR3A (0.58)
SCHEMBL23932558 0.77 RPS6KB1 (0.55) RPS6KB1CACNA1GCACNA1BKCNH2ATM
SCHEMBL22640026 0.77 DRD4 (0.57) PIK3CDPIK3CBKDM4EMAPTPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 RPS6KB1 316/4885PIK3CD 3553/4885PIK3CB 3338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.