SCHEMBL23964164

SCHEMBL23964164

FC(F)(F)c1ccc2nc(CN3CCN(c4ccccc4)CC3)[nH]c2c1

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 10/20 0.68
RPS6KB1 P23443 1/20 0.61
NPC1 O15118 1/20 0.57
GAA P10253 1/20 0.57
SLC2A1 P11166 2/20 0.54
HTR1A P08908 1/20 0.54
ADRA2C P18825 1/20 0.54
HTR2A P28223 1/20 0.54
IDO1 P14902 1/20 0.53
DGAT1 O75907 1/20 0.52
SOAT1 P35610 1/20 0.52
KCNH2 Q12809 1/20 0.52
GRM2 Q14416 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23964138 0.90 SLC2A1 (0.62) DRD4RPS6KB1NPC1GAASLC2A1
SCHEMBL23964186 0.83 RPS6KB1 (0.62) DRD4RPS6KB1IDO1DGAT1SOAT1
SCHEMBL8687149 0.82 DRD4 (0.74) DRD4NPC1GAAHTR1AADRA2C
SCHEMBL2421049 0.82 NPY5R (0.63) DGAT1SOAT1KCNH2
SCHEMBL23964235 0.82 RPS6KB1 (0.58) DRD4RPS6KB1IDO1KCNH2
SCHEMBL30041229 0.82 RPS6KB1 (0.58) DRD4RPS6KB1IDO1KCNH2
SCHEMBL4809921 0.81 DRD4 (1.00) DRD4NPC1GAAHTR1AADRA2C
Hydrochloric Acid SCHEMBL30040164 0.81 RPS6KB1 (0.57) DRD4RPS6KB1IDO1KCNH2
SCHEMBL23932547 0.80 RPS6KB1 (0.66) DRD4RPS6KB1SLC2A1DGAT1SOAT1
SCHEMBL8687581 0.80 DRD4 (0.76) DRD4NPC1GAAHTR1AADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 DRD4 4746/4885RPS6KB1 316/4885NPC1 3136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.