SCHEMBL23964257

SCHEMBL23964257

Cc1ncnc(N2CCN(Cc3nc4cc(Cl)ccc4o3)CC2)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.47
F10 P00742 1/20 0.46
HTT P42858 3/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
HRH4 Q9H3N8 2/20 0.43
ACHE P22303 1/20 0.42
BACE1 P56817 1/20 0.42
MAPT P10636 5/20 0.41
TP53 P04637 2/20 0.41
LMNA P02545 2/20 0.41
RPS6KB1 P23443 2/20 0.41
KDM4E B2RXH2 1/20 0.41
RECQL P46063 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ALDH1A1 P00352 1/20 0.41
NR2F2 P24468 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
HCRTR1 O43613 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30297611 0.93 SOS1 (0.57) SOS1F10HTTMEN1KMT2A
SCHEMBL23932566 0.93 SOS1 (0.57) SOS1F10HTTMEN1KMT2A
SCHEMBL23932546 0.87 KDM4E (0.45) HTTMEN1KMT2AACHEBACE1
SCHEMBL30040150 0.87 KDM4E (0.45) HTTMEN1KMT2AACHEBACE1
SCHEMBL23932495 0.86 MAPK1 (0.46) HTTMEN1KMT2AMAPTLMNA
SCHEMBL30041262 0.86 MAPK1 (0.46) HTTMEN1KMT2AMAPTLMNA
SCHEMBL30040810 0.85 RPS6KB1 (0.42) HTTKMT2AHRH4MAPTTP53
SCHEMBL25505769 0.85 CACNA1G (0.38) HTTKMT2AACHEBACE1MAPT
SCHEMBL23932502 0.85 RPS6KB1 (0.42) HTTKMT2AHRH4MAPTTP53
SCHEMBL25510924 0.84 LMNA (0.55) SOS1ACHEBACE1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed
WO-2021216665-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 SOS1 1100/4885F10 790/4885HTT 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.