Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | COMT | P21964 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23419232 | 0.78 | SSTR4 (0.41) | GAA | |
| SCHEMBL31505059 | 0.74 | KDM4E (0.50) | ALDH1A1L3MBTL1KDM4EKMT2ACOMT | |
| SCHEMBL2627824 | 0.74 | KDM4E (0.50) | ALDH1A1L3MBTL1KDM4EKMT2ACOMT | |
| SCHEMBL5038676 | 0.72 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1KDM4EKMT2ACOMT | |
| SCHEMBL15979318 | 0.72 | ESR1 (0.32) | ESR1ESR2TLR8 | |
| SCHEMBL22140286 | 0.71 | P2RX7 (0.33) | KDM4EESR1ESR2COMTGAA | |
| SCHEMBL24759749 | 0.71 | CYP3A4 (0.51) | ALDH1A1TSHRMAPTNPC1 | |
| SCHEMBL1331870 | 0.71 | KDM4E (0.43) | ALDH1A1L3MBTL1KDM4EKMT2ACOMT | |
| SCHEMBL755065 | 0.71 | KDM4E (0.43) | ALDH1A1L3MBTL1KDM4EKMT2ACOMT | |
| SCHEMBL29834150 | 0.71 | KDM4E (0.43) | ALDH1A1L3MBTL1KDM4EKMT2ACOMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11155547-B1 | Compounds for and methods of treating diseases | Alterity Therapeutics Limited (AU) | 2021-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11155547-B1 | Compounds for and methods of treating diseases | HTT, SNCA, PARK7 | ALDH1A1 2721/4885L3MBTL1 2678/4885KDM4E 1820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.