Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26172951 | 0.86 | MAP1LC3B (0.58) | CYP1A1CYP1A2MAP1LC3BALDH1A1ALOX15 | |
| SCHEMBL23964460 | 0.85 | MAP1LC3B (0.54) | CYP1A1CYP1A2MAP1LC3BALDH1A1ALOX15 | |
| SCHEMBL23964475 | 0.81 | ABCG2 (0.56) | MAP1LC3BALDH1A1ALOX15TSHRMAPK1 | |
| SCHEMBL31282322 | 0.79 | MAP1LC3B (0.59) | MAP1LC3BALDH1A1ALOX15TSHRMAPK1 | |
| SCHEMBL3787335 | 0.74 | MAP1LC3B (1.00) | CYP1A1CYP1A2MAP1LC3BALDH1A1ALOX15 | |
| SCHEMBL23964527 | 0.70 | MAP1LC3B (0.56) | MAP1LC3BALDH1A1ALOX15TSHRMAPK1 | |
| SCHEMBL15231356 | 0.70 | ABCG2 (0.66) | ABCB1 | |
| SCHEMBL6587812 | 0.69 | ALDH1A1 (0.59) | MAP1LC3BALDH1A1MAPK1MAPTHPGD | |
| SCHEMBL23964499 | 0.68 | MAP1LC3B (0.45) | MAP1LC3BALDH1A1ALOX15TSHRMAPK1 | |
| SCHEMBL19867238 | 0.68 | ALDH1A1 (0.67) | CYP1A2MAP1LC3BALDH1A1ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181744-A1 | COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES | FUDAN UNIVERSITY (CN) | 2023-06-15 | — | — | US | disclosed |
| US-20230181744-A1 | COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES | FUDAN UNIVERSITY (CN) | 2023-06-15 | — | — | US | disclosed |
| CN-115427396-A | Compounds for preventing or treating lipid metabolism-related diseases | 复旦大学 | 2022-12-02 | — | — | CN | disclosed |
| WO-2021213518-A1 | COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES | 复旦大学 (CN) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181744-A1 | COMPOUND FOR PREVENTING OR TREATING LIPID METABOLISM-RELATED DISEASES | MAP1LC3B, MAP1LC3A, SQSTM1 | CYP1A1 310/4885CYP1A2 192/4885MAP1LC3B 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.