Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23965805 | 0.86 | NPC1 (0.60) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL14394876 | 0.85 | NPC1 (0.65) | NPC1RAB9AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL31738384 | 0.84 | CYP1A2 (0.54) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL23965796 | 0.84 | NPC1 (0.58) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL23965785 | 0.84 | MAOA (0.52) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL31738383 | 0.84 | CYP1A2 (0.54) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1913680 | 0.78 | NPC1 (0.71) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5596285 | 0.74 | KDM4E (0.47) | NPC1RAB9ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL1913774 | 0.74 | NPC1 (0.61) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL17963016 | 0.73 | MAPT (0.65) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161830-B2 | 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same | FUJIFILM CORPORATION (JP) | 2021-11-02 | — | — | US | disclosed |
| CN-102120734-B | Method for preparing 2-(N-alkyl)aminobenzothiazole derivatives by using active alcohol as alkylating reagent | UNIV NANJING SCIENCE & TECH | 2013-08-07 | — | — | CN | disclosed |
| CN-102120734-A | Method for preparing 2-(N-alkyl)aminobenzothiazole derivatives by using active alcohol as alkylating reagent | UNIV NANJING SCIENCE & TECH | 2011-07-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161830-B2 | 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same | HAVCR2, HBS1L, PHKB | NPC1 1739/4885RAB9A 2878/4885KMT2A 2334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.