Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596753 | 0.82 | ILK (0.56) | KDM4ENPC1RAB9AALDH1A1CCNE1 | |
| SCHEMBL5596344 | 0.81 | RAB9A (0.46) | KDM4ENPC1RAB9AALDH1A1TP53 | |
| SCHEMBL5596942 | 0.80 | ILK (0.51) | KDM4ENPC1RAB9AALDH1A1TP53 | |
| SCHEMBL5596256 | 0.79 | NPC1 (0.54) | KDM4ENPC1RAB9AALDH1A1TP53 | |
| SCHEMBL5596406 | 0.78 | ILK (0.51) | KDM4ENPC1RAB9AALDH1A1TP53 | |
| SCHEMBL5596435 | 0.78 | ILK (0.40) | KDM4ENPC1RAB9AALDH1A1TP53 | |
| SCHEMBL5596495 | 0.76 | LTA4H (0.39) | KDM4ENPC1RAB9AALDH1A1TP53 | |
| SCHEMBL5596674 | 0.76 | NPC1 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5596418 | 0.76 | NPC1 (0.44) | KDM4ENPC1RAB9AALDH1A1TP53 | |
| SCHEMBL5596937 | 0.76 | ILK (0.53) | KDM4ENPC1RAB9AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |