Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.47 |
| ▸ | PRKX | P51817 | 1/20 | 0.47 |
| ▸ | NEK4 | P51957 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.47 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215893 | 0.88 | NOS3 (0.60) | MAOAMAOBROCK2MAP4K4PRKCG | |
| SCHEMBL23965829 | 0.87 | GAA (0.48) | ROCK2MAP4K4PRKCGLYNPRKACA | |
| SCHEMBL31738383 | 0.85 | CYP1A2 (0.54) | MAOAMAOBROCK2MAP4K4PRKCG | |
| SCHEMBL23965796 | 0.85 | NPC1 (0.58) | ROCK2MAP4K4PRKCGLYNPRKACA | |
| SCHEMBL31738384 | 0.85 | CYP1A2 (0.54) | MAOAMAOBROCK2MAP4K4PRKCG | |
| SCHEMBL23965797 | 0.84 | NPC1 (0.56) | MAOAMAOBSMN1; SMN2KDM4EMAPT | |
| SCHEMBL5256491 | 0.81 | ROCK2 (0.64) | ROCK2MAP4K4PRKCGLYNPRKACA | |
| SCHEMBL7984841 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EMAPTHPGDMEN1 | |
| SCHEMBL5305295 | 0.74 | NPC1 (0.70) | MAOBROCK2MAP4K4PRKCGLYN | |
| SCHEMBL12373232 | 0.73 | MAPK14 (0.58) | ROCK2MAP4K4PRKCGLYNPRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161830-B2 | 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same | FUJIFILM CORPORATION (JP) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161830-B2 | 4-pyridone compound or salt thereof, and pharmaceutical composition and formulation including same | HAVCR2, HBS1L, PHKB | MAOA 3838/4885MAOB 2002/4885ROCK2 3716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.