Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | AKR1B1 | P15121 | 14/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10007138 | 0.84 | MAPT (0.79) | MAPTAKR1B1KMT2APOLBALOX15 | |
| SCHEMBL23966572 | 0.84 | RECQL (0.57) | MAPTAKR1B1KMT2APOLBALOX15 | |
| SCHEMBL9327258 | 0.84 | MAPT (0.78) | MAPTAKR1B1KMT2APOLBALOX15 | |
| SCHEMBL6890822 | 0.81 | MAPT (1.00) | MAPTAKR1B1KMT2APOLBALOX15 | |
| SCHEMBL8957310 | 0.80 | KMT2A (0.77) | MAPTAKR1B1KMT2APTGDR2TSHR | |
| SCHEMBL11172701 | 0.78 | MAPT (0.61) | MAPTAKR1B1KMT2APOLB | |
| SCHEMBL23914950 | 0.78 | MAPT (0.61) | MAPTAKR1B1KMT2APOLB | |
| SCHEMBL15597471 | 0.78 | MAPT (0.68) | MAPTKMT2APOLBTSHR | |
| SCHEMBL8128443 | 0.78 | MAPT (0.68) | MAPTAKR1B1KMT2APOLBALOX15 | |
| SCHEMBL8957218 | 0.78 | MAPT (0.68) | MAPTAKR1B1KMT2APOLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |