Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 12/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10007138 | 0.88 | MAPT (0.79) | MAPTRECQLALOX15AKR1B1POLB | |
| SCHEMBL9327258 | 0.88 | MAPT (0.78) | MAPTALOX15AKR1B1POLBKMT2A | |
| SCHEMBL23914750 | 0.86 | MAPT (0.75) | MAPTRECQLALOX15AKR1B1POLB | |
| SCHEMBL8957310 | 0.84 | KMT2A (0.77) | MAPTAKR1B1KMT2AALDH1A1TSHR | |
| SCHEMBL10533803 | 0.83 | MAPT (0.71) | MAPTRECQLALOX15AKR1B1POLB | |
| SCHEMBL23915521 | 0.82 | MAPT (0.69) | MAPTALOX15AKR1B1POLBKMT2A | |
| SCHEMBL15597471 | 0.81 | MAPT (0.68) | MAPTPOLBKMT2AALDH1A1TSHR | |
| SCHEMBL8957218 | 0.81 | MAPT (0.68) | MAPTALOX15AKR1B1POLBKMT2A | |
| SCHEMBL23966567 | 0.81 | MAPT (0.68) | MAPTALOX15AKR1B1POLBKMT2A | |
| SCHEMBL8128443 | 0.81 | MAPT (0.68) | MAPTALOX15AKR1B1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082079-A1 | Low affinity screening method | GRAFFINITY PHARMACEUTICALS AG. (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1360489-A1 | LOW AFFINITY SCREENING METHOD | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002063299-A1 | LOW AFFINITY SCREENING METHOD | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-08-15 | — | — | WO | disclosed |