Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.78 |
| ▸ | AKR1B1 | P15121 | 12/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | CMA1 | P23946 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23914750 | 0.89 | MAPT (0.75) | MAPTAKR1B1ALOX15TSHRCMA1 | |
| SCHEMBL6890822 | 0.88 | MAPT (1.00) | MAPTAKR1B1ALOX15TSHRPOLB | |
| SCHEMBL23915521 | 0.87 | MAPT (0.69) | MAPTAKR1B1ALOX15TSHRPOLB | |
| SCHEMBL8957310 | 0.86 | KMT2A (0.77) | MAPTAKR1B1TSHRKMT2A | |
| SCHEMBL24076967 | 0.86 | ALOX15 (1.00) | MAPTAKR1B1ALOX15TSHRCMA1 | |
| SCHEMBL10007138 | 0.85 | MAPT (0.79) | MAPTAKR1B1ALOX15POLBKMT2A | |
| SCHEMBL23909094 | 0.84 | MAPT (0.64) | MAPTAKR1B1ALOX15TSHRPOLB | |
| SCHEMBL8957218 | 0.84 | MAPT (0.68) | MAPTAKR1B1ALOX15TSHRPOLB | |
| SCHEMBL8128443 | 0.84 | MAPT (0.68) | MAPTAKR1B1ALOX15TSHRPOLB | |
| SCHEMBL23966567 | 0.84 | MAPT (0.68) | MAPTAKR1B1ALOX15TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304557-A | Aldose reductase inhibitor | PFIZER INC. (US) | 1994-04-19 | — | — | US | disclosed |