Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 5/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.38 |
| ▸ | XDH | P47989 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909013 | 0.88 | XDH (0.38) | IKBKETBK1XDH | |
| SCHEMBL23966834 | 0.88 | XDH (0.38) | IKBKETBK1XDH | |
| SCHEMBL23915306 | 0.85 | XDH (0.36) | IKBKETBK1XDH | |
| SCHEMBL23909001 | 0.84 | XDH (0.38) | IKBKETBK1XDH | |
| SCHEMBL23915309 | 0.83 | XDH (0.37) | IKBKETBK1XDH | |
| SCHEMBL23909131 | 0.80 | XDH (0.36) | IKBKETBK1XDH | |
| SCHEMBL23914584 | 0.78 | XDH (0.34) | IKBKETBK1XDH | |
| SCHEMBL23914757 | 0.77 | XDH (0.36) | IKBKETBK1XDH | |
| SCHEMBL23914583 | 0.76 | XDH (0.35) | IKBKETBK1XDH | |
| SCHEMBL23966550 | 0.76 | CNR2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |