Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23966550 | 0.89 | CNR2 (0.32) | CNR2 | |
| SCHEMBL23914853 | 0.88 | XDH (0.38) | XDHHTTHSD17B10IKBKETBK1 | |
| SCHEMBL23966809 | 0.88 | IKBKE (0.38) | XDHIKBKETBK1 | |
| SCHEMBL23914849 | 0.86 | XDH (0.37) | XDHHTTHSD17B10IKBKE | |
| SCHEMBL23908843 | 0.86 | XDH (0.39) | XDHHTTHSD17B10IKBKETBK1 | |
| SCHEMBL23914609 | 0.85 | XDH (0.38) | XDHHTTHSD17B10IKBKETBK1 | |
| SCHEMBL23966548 | 0.78 | DGAT1 (0.34) | CNR2 | |
| SCHEMBL23915573 | 0.77 | SCN9A (0.33) | CNR2 | |
| SCHEMBL23909131 | 0.76 | XDH (0.36) | XDHIKBKETBK1S1PR1 | |
| SCHEMBL23909013 | 0.76 | XDH (0.38) | XDHIKBKETBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |