Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23966834 | 0.89 | XDH (0.38) | CNR2 | |
| SCHEMBL23966548 | 0.89 | DGAT1 (0.34) | CNR2PDE4B | |
| SCHEMBL23915573 | 0.88 | SCN9A (0.33) | CNR2PDE4B | |
| SCHEMBL23966549 | 0.85 | DGAT1 (0.34) | CNR2PDE4B | |
| SCHEMBL23914853 | 0.77 | XDH (0.38) | — | |
| SCHEMBL23908843 | 0.76 | XDH (0.39) | — | |
| SCHEMBL23966809 | 0.76 | IKBKE (0.38) | — | |
| SCHEMBL23914609 | 0.75 | XDH (0.38) | — | |
| SCHEMBL23914849 | 0.75 | XDH (0.37) | — | |
| SCHEMBL23966547 | 0.72 | SMN1; SMN2 (0.36) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |