Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | APLNR | P35414 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CD4 | P01730 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29402099 | 0.93 | TSHR (0.53) | TSHRKDM4EALDH1A1LMNATDP1 | |
| SCHEMBL29036131 | 0.89 | TSHR (0.49) | TSHRKDM4EALDH1A1LMNATDP1 | |
| Quinoline SCHEMBL27810303 | 0.88 | ALDH1A1 (0.47) | TSHRKDM4EALDH1A1LMNATDP1 | |
| SCHEMBL28879101 | 0.88 | TSHR (0.48) | TSHRKDM4EALDH1A1LMNATDP1 | |
| SCHEMBL5091012 | 0.87 | TSHR (0.54) | TSHRKDM4EALDH1A1LMNATDP1 | |
| Sulfuric Acid SCHEMBL62247 | 0.85 | FDPS (0.43) | TSHRALDH1A1HTTL3MBTL1APLNR | |
| Sulfuric Acid SCHEMBL27798882 | 0.85 | FDPS (0.43) | TSHRALDH1A1HTTL3MBTL1APLNR | |
| SCHEMBL29859619 | 0.84 | ALDH1A1 (0.46) | TSHRKDM4EALDH1A1LMNATDP1 | |
| SCHEMBL1274385 | 0.83 | FDPS (0.42) | TSHRALDH1A1APLNRPOLBAGTR1 | |
| SCHEMBL29859863 | 0.81 | ALDH1A1 (0.46) | TSHRKDM4EALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082540-B | Synthesis process of low-volatile odorless polyvinyl butyral resin powder | 江苏奥天利新材料有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-114849786-B | Imidazole sulfonic acid ionic liquid-based palladium phosphine complex catalyst for synthesizing methyl propionate through ethylene hydro-methyl esterification | 中国科学院过程工程研究所 | 2023-09-05 | — | — | CN | claimed |
| CN-116283634-A | Aromatic diamine chain extender containing ester group and preparation method thereof | 江苏湘园化工有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116082540-A | Synthesis process of low-volatile odorless polyvinyl butyral resin powder | 江苏奥天利新材料有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-114849786-A | Imidazole sulfonic acid ionic liquid based palladium-phosphine complex catalyst for synthesizing methyl propionate by ethylene methyl hydrogen esterification | 中国科学院过程工程研究所 | 2022-08-05 | — | — | CN | claimed |
| CN-114849786-B | Imidazole sulfonic acid ionic liquid-based palladium phosphine complex catalyst for synthesizing methyl propionate through ethylene hydro-methyl esterification | 中国科学院过程工程研究所 | 2023-09-05 | — | — | CN | disclosed |
| CN-116283634-A | Aromatic diamine chain extender containing ester group and preparation method thereof | 江苏湘园化工有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116178315-A | Method for efficiently converting chitosan into 5-hydroxymethylfurfural by using sulfonated ionic liquid | 集美大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-114849786-A | Imidazole sulfonic acid ionic liquid based palladium-phosphine complex catalyst for synthesizing methyl propionate by ethylene methyl hydrogen esterification | 中国科学院过程工程研究所 | 2022-08-05 | — | — | CN | disclosed |
| US-9399613-B2 | Direct carbon dioxide hydrogenation to formic acid in acidic media | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-07-26 | — | — | US | disclosed |
| US-20160016875-A1 | DIRECT CARBON DIOXIDE HYDROGENATION TO FORMIC ACID IN ACIDIC MEDIA | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) EPFL-TTO (CH) | 2016-01-21 | — | — | US | disclosed |
| EP-2767530-A1 | Direct carbon dioxide hydrogenation to formic acid in acidic media | EOS Holding SA (CH) | 2014-08-20 | — | — | EP | disclosed |
| US-8027150-B2 | Conductive polymer solid electrolytic capacitor | KANEKA CORPORATION (JP) | 2011-09-27 | — | — | US | disclosed |
| US-20080218942-A1 | Conductive polymer solid electrolytic capacitor | KANEKA CORPORATION (JP) | 2008-09-11 | — | — | US | disclosed |