Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29402099 | 0.90 | TSHR (0.53) | TSHRALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL2396708 | 0.87 | TSHR (0.50) | TSHRALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL30564825 | 0.84 | ALDH1A1 (0.47) | TSHRALDH1A1KDM4EMAPTTDP1 | |
| Sulfuric Acid SCHEMBL2857065 | 0.83 | FDPS (0.47) | TSHRALDH1A1HTTMAPK1FDPS | |
| Sulfuric Acid SCHEMBL28074354 | 0.83 | FDPS (0.47) | TSHRALDH1A1HTTMAPK1FDPS | |
| Sulfuric Acid SCHEMBL28845974 | 0.83 | FDPS (0.47) | TSHRALDH1A1HTTMAPK1FDPS | |
| SCHEMBL29036131 | 0.83 | TSHR (0.49) | TSHRALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL29859863 | 0.83 | ALDH1A1 (0.46) | TSHRALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL2998201 | 0.82 | KDM4E (0.51) | TSHRALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL28879101 | 0.82 | TSHR (0.48) | TSHRALDH1A1KDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114849786-B | Imidazole sulfonic acid ionic liquid-based palladium phosphine complex catalyst for synthesizing methyl propionate through ethylene hydro-methyl esterification | 中国科学院过程工程研究所 | 2023-09-05 | — | — | CN | claimed |
| CN-114849786-A | Imidazole sulfonic acid ionic liquid based palladium-phosphine complex catalyst for synthesizing methyl propionate by ethylene methyl hydrogen esterification | 中国科学院过程工程研究所 | 2022-08-05 | — | — | CN | claimed |
| US-20230279560-A1 | CYCLIC COMPOUNDS AS AROMA CHEMICALS | BASF SE (DE) | 2023-09-07 | — | — | US | disclosed |
| CN-114849786-B | Imidazole sulfonic acid ionic liquid-based palladium phosphine complex catalyst for synthesizing methyl propionate through ethylene hydro-methyl esterification | 中国科学院过程工程研究所 | 2023-09-05 | — | — | CN | disclosed |
| EP-4189141-A1 | CYCLIC COMPOUNDS AS AROMA CHEMICALS | BASF SE (DE) | 2023-06-07 | — | — | EP | disclosed |
| CN-114849786-A | Imidazole sulfonic acid ionic liquid based palladium-phosphine complex catalyst for synthesizing methyl propionate by ethylene methyl hydrogen esterification | 中国科学院过程工程研究所 | 2022-08-05 | — | — | CN | disclosed |
| US-20080139710-A1 | Conductive Composition, Conductive Molded Body and Conductive Gel Composition, and Method for Producing the Same | KANEKA CORPORATION (JP) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279560-A1 | CYCLIC COMPOUNDS AS AROMA CHEMICALS | C1S, VDAC2, VDAC3 | TSHR 4215/4885ALDH1A1 1019/4885KDM4E 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.