Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23967357 | 0.94 | SIGMAR1 (0.39) | MAPTKDM4ENPSR1LMNAALDH1A1 | |
| SCHEMBL22164696 | 0.93 | LMNA (0.42) | MAPTKDM4ENPSR1LMNAALDH1A1 | |
| SCHEMBL22173770 | 0.92 | LMNA (0.38) | MAPTKDM4ENPSR1LMNAALDH1A1 | |
| SCHEMBL22164678 | 0.92 | GRM2 (0.37) | MAPTKDM4ENPSR1LMNAALDH1A1 | |
| SCHEMBL22164683 | 0.92 | HTR1A (0.35) | MAPTKDM4ENPSR1LMNAALDH1A1 | |
| SCHEMBL22165535 | 0.90 | VKORC1 (0.38) | MAPTKDM4ENPSR1LMNAALDH1A1 | |
| SCHEMBL22164777 | 0.90 | LMNA (0.35) | MAPTKDM4ENPSR1LMNAALDH1A1 | |
| SCHEMBL22165377 | 0.89 | DRD4 (0.37) | KDM4EALDH1A1TDP1HTR1ADRD4 | |
| SCHEMBL23967419 | 0.89 | HTR1A (0.39) | MAPTKDM4ENPSR1LMNAALDH1A1 | |
| SCHEMBL22165531 | 0.86 | ABCB1 (0.40) | MAPTKDM4EALDH1A1HTTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903786-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME FOR ENHANCING ANTICANCER ACTIVITY | Holosmedic (KR) | 2021-11-03 | — | — | EP | disclosed |