Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22173770 | 0.91 | LMNA (0.38) | LMNATHRBHTR1AKDM4EALDH1A1 | |
| SCHEMBL23967357 | 0.91 | SIGMAR1 (0.39) | LMNATHRBHTR1AKDM4EALDH1A1 | |
| SCHEMBL22164696 | 0.90 | LMNA (0.42) | LMNATHRBHTR1AKDM4EALDH1A1 | |
| SCHEMBL23967353 | 0.90 | MAPT (0.37) | LMNATHRBHTR1AKDM4EALDH1A1 | |
| SCHEMBL22164683 | 0.89 | HTR1A (0.35) | VKORC1LMNATHRBHTR1AKDM4E | |
| SCHEMBL22164678 | 0.89 | GRM2 (0.37) | LMNATHRBHTR1AKDM4EALDH1A1 | |
| SCHEMBL22164777 | 0.87 | LMNA (0.35) | LMNATHRBHTR1AKDM4EALDH1A1 | |
| SCHEMBL22165377 | 0.86 | DRD4 (0.37) | PIK3CDPIK3CAPIK3CBPIK3CGSIRT2 | |
| SCHEMBL23967419 | 0.86 | HTR1A (0.39) | LMNAHTR1AKDM4EALDH1A1MAPT | |
| SCHEMBL22164726 | 0.84 | HSD17B10 (0.36) | HTR1AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12139491-B2 | Diketopiperazine derivatives as calcium ATPase inhibitor for enhancing anticancer activity | HOLOSMEDIC (KR) | 2024-11-12 | — | — | US | disclosed |
| EP-3903786-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME FOR ENHANCING ANTICANCER ACTIVITY | Holosmedic (KR) | 2021-11-03 | — | — | EP | disclosed |
| WO-2020139044-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME FOR ENHANCING ANTICANCER ACTIVITY | 홀로스메딕 주식회사 | 2020-07-02 | — | — | WO | disclosed |
| WO-2020139044-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME FOR ENHANCING ANTICANCER ACTIVITY | 홀로스메딕 주식회사 | 2020-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12139491-B2 | Diketopiperazine derivatives as calcium ATPase inhibitor for enhancing anticancer activity | ATP1A1, ATP1B1, ATP1B2 | VKORC1 2958/4885LMNA 4218/4885PIK3CD 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.