SCHEMBL23967805

SCHEMBL23967805

Cc1ccccc1N(I)c1cccc2c1sc1c(C(C)(C)C)cccc12

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
KIF11 P52732 1/20 0.32
HSD17B1 P14061 2/20 0.31
HSD17B2 P37059 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650237 0.90 KIF11 (0.34) KIF11
SCHEMBL20650374 0.89 GABRA1 (0.36) GABRA1GABRB2KIF11
SCHEMBL20650207 0.88 KIF11 (0.31) KIF11HSD17B1HSD17B2
SCHEMBL20650819 0.87
SCHEMBL20649761 0.85 KIF11 (0.31) KIF11
SCHEMBL20172909 0.84 GABRA1 (0.37) GABRA1GABRB2KIF11HSD17B1HSD17B2
SCHEMBL20650240 0.83 SIGMAR1 (0.30) KIF11
SCHEMBL20650238 0.83 KMT2A (0.31) GABRA1GABRB2KIF11
SCHEMBL20650281 0.82 GPR3 (0.39)
SCHEMBL23967665 0.82 HDAC3 (0.33) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed