SCHEMBL23967806

SCHEMBL23967806

Cc1ccc(N(C)c2cccc3c2sc2c(F)cccc23)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21021500 0.87 CYP1A2 (0.38) CYP1A2CYP2A6MAPTNPSR1
SCHEMBL20172885 0.86 ACHE (0.37) CYP1A2CYP2A6MAPTNPSR1
SCHEMBL20650832 0.85 CYP1A2 (0.31) CYP1A2CYP2A6
SCHEMBL21020022 0.83 NR1H2 (0.34) NPSR1
SCHEMBL21020590 0.82 MAPT (0.38) CYP1A2CYP2A6KDM4EMAPTNPSR1
SCHEMBL21020322 0.82 ALDH1A1 (0.32)
SCHEMBL21020588 0.82 LMNA (0.33) CYP1A2CYP2A6MAPT
SCHEMBL21020311 0.82 MEN1 (0.36) CYP1A2CYP2A6MAPTNPSR1
SCHEMBL21021504 0.82 HSD17B1 (0.32) CYP1A2CYP2A6NPSR1
SCHEMBL21020464 0.82 CYP1A2 (0.30) CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed