Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23965677 | 0.85 | TRPA1 (0.41) | MAPTNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL8875910 | 0.79 | MAPT (0.51) | MAPTNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL23967920 | 0.79 | CNR1 (0.43) | MAPTCNR2CNR1LPLLIPG | |
| SCHEMBL20077276 | 0.79 | SMN1; SMN2 (0.53) | MAPTNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL429772 | 0.78 | PNMT (0.61) | MAPTCNR2CNR1SIGMAR1PNMT | |
| SCHEMBL8338463 | 0.75 | NPC1 (0.58) | MAPTNPC1CASP3RAB9ASMN1; SMN2 | |
| Bicarbonate SCHEMBL3431862 | 0.74 | PNMT (0.52) | MAPTSMN1; SMN2CNR2CNR1SIGMAR1 | |
| SCHEMBL4462445 | 0.73 | CYP3A4 (0.50) | MAPTNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL10948799 | 0.73 | NPC1 (0.47) | MAPTNPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL20077738 | 0.73 | SMN1; SMN2 (0.57) | MAPTNPC1CASP3RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903581-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS I | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |
| EP-3903584-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS IV | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |