SCHEMBL23967920

SCHEMBL23967920

CCCc1ccc(C(C)=N)c(F)c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
RARB P10826 2/20 0.40
RARA P10276 1/20 0.40
RARG P13631 1/20 0.40
LPL P06858 1/20 0.36
LIPG Q9Y5X9 1/20 0.36
ALOX5 P09917 1/20 0.35
MAOB P27338 1/20 0.35
PDK2 Q15119 1/20 0.35
MCL1 Q07820 1/20 0.34
PPARA Q07869 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
XBP1 P17861 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16684105 0.82 MAOB (0.51) CNR1CNR2RARBRARARARG
SCHEMBL24358443 0.82 CNR1 (0.43) CNR1CNR2RARBRARARARG
SCHEMBL6550099 0.80 RARB (0.59) CNR1CNR2RARBRARARARG
SCHEMBL15289772 0.80 LOXL2 (0.39) MAOB
SCHEMBL23967871 0.79 MAPT (0.44) CNR1CNR2LPLLIPGMAPT
SCHEMBL29893781 0.77 DGAT1 (0.51) CNR1CNR2RARBRARARARG
SCHEMBL7735953 0.77 RARB (0.46) CNR1CNR2RARBRARARARG
SCHEMBL7738951 0.77 RARB (0.60) RARBRARARARGMCL1PPARA
SCHEMBL7219535 0.75 NPC1 (0.44) RARBRARARARGPPARAMAPT
SCHEMBL530305 0.74 CNR1 (0.48) CNR1CNR2LPLLIPGALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3903584-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS IV BASF SE (DE) 2021-11-03 EP disclosed
EP-3903582-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II BASF SE (DE) 2021-11-03 EP disclosed