Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.34 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787369 | 0.81 | CES2 (0.46) | KDM1ACES2NOTUMDGAT1EPRS1 | |
| SCHEMBL29451092 | 0.77 | EPRS1 (0.51) | KDM1ACES2DGAT1EPRS1 | |
| SCHEMBL257339 | 0.77 | EPRS1 (0.51) | KDM1ACES2DGAT1EPRS1 | |
| SCHEMBL28299420 | 0.77 | KDM1A (0.42) | KDM1ACES2NOTUMDGAT1EPRS1 | |
| SCHEMBL25532291 | 0.76 | CES2 (0.47) | KDM1ACES2NOTUMDGAT1EPRS1 | |
| SCHEMBL30864218 | 0.75 | KDM1A (0.50) | KDM1ACES2NOTUMEPRS1NPFFR1 | |
| SCHEMBL6267032 | 0.75 | KDM1A (0.50) | KDM1ACES2NOTUMEPRS1NPFFR1 | |
| SCHEMBL17159522 | 0.75 | CES2 (0.47) | KDM1ACES2NOTUMDGAT1EPRS1 | |
| SCHEMBL23205445 | 0.75 | DGAT1 (0.55) | KDM1ACES2DGAT1 | |
| SCHEMBL6888239 | 0.74 | KDM1A (0.44) | KDM1ACES2DGAT1EPRS1NPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903582-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS II | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |
| EP-3903584-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS IV | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |