Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | ACACB | O00763 | 4/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | ACACA | Q13085 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388983 | 0.90 | KMT2A (0.82) | ATMKMT2AMEN1ACACBCTSB | |
| SCHEMBL388984 | 0.90 | KMT2A (0.82) | ATMKMT2AMEN1ACACBCTSB | |
| SCHEMBL28057007 | 0.90 | KMT2A (0.82) | ATMKMT2AMEN1ACACBCTSB | |
| Dimethylamine SCHEMBL10425391 | 0.88 | KMT2A (0.79) | ATMKMT2AMEN1ACACBCTSB | |
| SCHEMBL25964562 | 0.86 | KMT2A (0.70) | ATMKMT2AMEN1ACACBMAPK1 | |
| SCHEMBL16604417 | 0.86 | KMT2A (0.70) | ATMKMT2AMEN1ACACBMAPK1 | |
| SCHEMBL16606603 | 0.85 | KMT2A (0.63) | ATMKMT2AMEN1ACACBMAPK1 | |
| SCHEMBL30309096 | 0.85 | KMT2A (0.68) | ATMKMT2AMEN1ACACBMAPK1 | |
| SCHEMBL18011186 | 0.85 | KMT2A (0.68) | ATMKMT2AMEN1ACACBCTSB | |
| SCHEMBL16606805 | 0.85 | KMT2A (0.68) | ATMKMT2AMEN1ACACBCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11160886-B2 | Method for labeling of sensitive and thermosensitive targeting biomolecules with technetium based compounds | BRACCO IMAGING SPA (IT) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11160886-B2 | Method for labeling of sensitive and thermosensitive targeting biomolecules with technetium based compounds | PNP, TK1, NT5E | ATM 2664/4885KMT2A 4465/4885MEN1 999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.