SCHEMBL23969104

SCHEMBL23969104

N#CC(C#N)=C1c2cc(-c3cccc(C(F)(F)F)c3)c(C#N)cc2-c2cc(C#N)c(-c3cccc(C(F)(F)F)c3)cc21

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.43
CTSS P25774 4/20 0.43
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
CTSK P43235 5/20 0.38
KCNH2 Q12809 1/20 0.38
AR P10275 3/20 0.37
RORC P51449 1/20 0.37
RORB Q92753 1/20 0.37
SCN9A Q15858 1/20 0.37
PGR P06401 1/20 0.36
CES2 O00748 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2B Q13224 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21917306 1.00 XDH (0.43) XDHCTSSKDM4EALDH1A1GAA
SCHEMBL23969036 0.86 CYP11B1 (0.33) XDHCTSSALDH1A1GAACTSK
SCHEMBL21917103 0.85 KIF11 (0.42) XDHALDH1A1ARPGRPTGDR2
SCHEMBL21917429 0.85 KIF11 (0.42) XDHALDH1A1ARPGRPTGDR2
SCHEMBL23968915 0.84 RXRA (0.39) XDHARPGR
SCHEMBL12118000 0.84 CTSS (0.42) XDHCTSSALDH1A1GAACTSK
SCHEMBL12198263 0.84 CTSS (0.42) XDHCTSSALDH1A1GAACTSK
SCHEMBL21917668 0.82 GRM5 (0.41) KDM4EALDH1A1GAASCN9A
SCHEMBL21917340 0.82 GRM5 (0.41) KDM4EALDH1A1GAASCN9A
SCHEMBL21917302 0.82 RXRA (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11165025-B2 Compound and organic electronic element comprising same LG CHEM, LTD. 2021-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11165025-B2 Compound and organic electronic element comprising same OR10J3, ESR1, ETV6 XDH 716/4885CTSS 4077/4885KDM4E 664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.