Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969391 | 0.84 | TAAR1 (0.37) | TAAR1MEN1KMT2A | |
| SCHEMBL23969340 | 0.84 | TAAR1 (0.37) | TAAR1MEN1KMT2A | |
| SCHEMBL22175858 | 0.79 | L3MBTL4 (0.38) | — | |
| SCHEMBL22175863 | 0.78 | SIGMAR1 (0.37) | MEN1KMT2A | |
| SCHEMBL22176523 | 0.78 | SIGMAR1 (0.37) | MEN1KMT2A | |
| SCHEMBL22175908 | 0.78 | SIGMAR1 (0.37) | MEN1KMT2A | |
| SCHEMBL23969232 | 0.77 | HRH4 (0.34) | MEN1KMT2A | |
| SCHEMBL22175868 | 0.74 | GABRG2 (0.31) | — | |
| SCHEMBL23969349 | 0.73 | CNR1 (0.38) | KMT2A | |
| SCHEMBL22176371 | 0.73 | SIGMAR1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903788-A1 | PYRAZOLO[1,5-A]PYRIMIDINE MACROCYCLIC COMPOUND | Taisho Pharmaceutical Co., Ltd. (JP) | 2021-11-03 | — | — | EP | disclosed |