Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2396935 | 0.88 | MAPT (0.47) | MAPTABCB1TP53POLBSMN1; SMN2 | |
| SCHEMBL2365024 | 0.84 | MAPT (0.51) | MAPTABCB1TP53POLBSMN1; SMN2 | |
| SCHEMBL7934076 | 0.70 | MAPT (0.41) | MAPTTP53ACLYPOLBSMN1; SMN2 | |
| SCHEMBL2400241 | 0.69 | MAPT (0.52) | MAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL2396967 | 0.67 | EPHX2 (0.48) | MAPTTP53POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL30530178 | 0.67 | SLC6A9 (0.71) | MAPTSMN1; SMN2SLC6A9SLC6A5ALDH1A1 | |
| SCHEMBL3238013 | 0.66 | ALDH1A1 (0.46) | MAPTSMN1; SMN2ALDH1A1LMNAS1PR3 | |
| SCHEMBL2397135 | 0.66 | TP53 (0.46) | MAPTTP53POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL28466269 | 0.66 | HPGDS (0.72) | MAPTSMN1; SMN2SLC6A9SLC6A5ALDH1A1 | |
| SCHEMBL28466273 | 0.66 | SLC6A9 (0.68) | MAPTSMN1; SMN2SLC6A9SLC6A5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237528-A1 | COMPOSITIONS AND METHODS COMPRISING IMIDAZOLE AND TRIAZOLE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237528-A1 | COMPOSITIONS AND METHODS COMPRISING IMIDAZOLE AND TRIAZOLE DERIVATIVES | CFTR, PKD1, PKD2 | MAPT 4644/4885ABCB1 24/4885TP53 919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.