Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20425022 | 0.98 | RORC (0.49) | RORCACHEMEN1KMT2AAOC3 | |
| SCHEMBL30722324 | 0.85 | MEN1 (0.49) | RORCACHEMEN1KMT2AAOC3 | |
| SCHEMBL10063435 | 0.84 | MEN1 (0.50) | RORCACHEMEN1KMT2AAOC3 | |
| SCHEMBL27767066 | 0.84 | HDAC3 (0.50) | ACHEMEN1KMT2ANPC1RAB9A | |
| SCHEMBL20425037 | 0.82 | GPR119 (0.51) | RORCACHEMEN1KMT2AAOC3 | |
| SCHEMBL34462083 | 0.81 | RORC (0.50) | RORCACHEMEN1KMT2AAOC3 | |
| SCHEMBL27793296 | 0.81 | GPR119 (0.61) | ACHEPTPN11CKS1BSKP1SKP2 | |
| SCHEMBL3607524 | 0.80 | POLB (0.66) | AOC3PTPN11POLBHDAC6KDM4E | |
| SCHEMBL20425044 | 0.79 | KDM4E (0.48) | AOC3PTPN11NPC1RAB9APOLB | |
| SCHEMBL29562721 | 0.79 | KDM4E (0.66) | RORCMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573974-B1 | RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2024-09-18 | — | — | EP | disclosed |
| US-11974997-B2 | RORgamma modulators and uses thereof | GENFIT (FR) | 2024-05-07 | — | — | US | disclosed |
| US-20220133716-A1 | RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2022-05-05 | — | — | US | disclosed |
| US-20220133716-A1 | RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2022-05-05 | — | — | US | disclosed |
| US-11160801-B2 | RORgamma modulators and uses thereof | GENFIT (FR) | 2021-11-02 | — | — | US | disclosed |
| US-11160801-B2 | RORgamma modulators and uses thereof | GENFIT (FR) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220133716-A1 | RORGAMMA MODULATORS AND USES THEREOF | RORB, RORC, RORA | RORC 2/4885ACHE 4073/4885MEN1 3748/4885 |
| US-11974997-B2 | RORgamma modulators and uses thereof | RORB, RORC, RORA | RORC 2/4885ACHE 4073/4885MEN1 3748/4885 |
| US-11160801-B2 | RORgamma modulators and uses thereof | RORB, RORC, RORA | RORC 2/4885ACHE 4073/4885MEN1 3748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.