Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 14/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21848402 | 0.88 | HSD11B1 (0.44) | HSD11B1MEN1KMT2AOPRM1 | |
| SCHEMBL24097137 | 0.83 | AKR1C1 (0.47) | HSD11B1CYP2D6MEN1KMT2AOPRM1 | |
| SCHEMBL28653670 | 0.83 | AKR1C1 (0.51) | CYP2D6MEN1KMT2ASIGMAR1 | |
| SCHEMBL30731583 | 0.82 | AKR1C1 (0.50) | HSD11B1CYP2D6MEN1KMT2ASIGMAR1 | |
| SCHEMBL23969611 | 0.82 | AKR1C1 (0.50) | HSD11B1CYP2D6MEN1KMT2ASIGMAR1 | |
| SCHEMBL31572848 | 0.74 | ALDH1A1 (0.41) | MEN1KMT2AMAPT | |
| SCHEMBL30809222 | 0.73 | ALDH1A1 (0.41) | MEN1KMT2AMAPT | |
| SCHEMBL11073957 | 0.73 | KMT2A (0.51) | MEN1KMT2AMAPT | |
| SCHEMBL7380213 | 0.72 | HSD11B1 (0.45) | HSD11B1MEN1KMT2AOPRM1 | |
| SCHEMBL426217 | 0.71 | ALDH1A1 (0.50) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2022-01-27 | — | — | US | disclosed |
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161859-B2 | Cu- and Ni-catalyzed decarboxylative borylation reactions | PCSK9, LIPA, ACSL3 | HSD11B1 644/4885CYP2D6 1922/4885MEN1 2765/4885 |
| US-20220024949-A1 | CU-AND NI-CATALYZED DECARBOXYLATIVE BORYLATION REACTIONS | PCSK9, PCSK7, PCSK6 | HSD11B1 589/4885CYP2D6 1786/4885MEN1 2960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.