Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.52 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170713 | 0.89 | NAAA (0.58) | NAAAPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL27472305 | 0.85 | PLAAT3 (0.60) | NAAAPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL28874674 | 0.84 | PLAAT3 (0.50) | PLAAT3PLAAT5PLAAT2PLAAT4SMN1; SMN2 | |
| SCHEMBL19612688 | 0.82 | NAAA (0.56) | NAAAPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL7829175 | 0.82 | SMN1; SMN2 (0.67) | NAAAPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL18126611 | 0.81 | MAPT (0.66) | NAAAPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL19612671 | 0.81 | NAAA (0.56) | NAAAPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL6819889 | 0.80 | MAPT (0.63) | PLAAT3PLAAT5PLAAT2PLAAT4SMN1; SMN2 | |
| SCHEMBL11037045 | 0.79 | PLAAT3 (0.58) | NAAAPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL3891167 | 0.79 | PLAAT3 (0.57) | NAAAPLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |