Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969673 | 0.81 | ATM (0.37) | ATMTDP1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL19624772 | 0.70 | AKT1 (0.39) | TDP1SMN1; SMN2KDM4EMAPTLMNA | |
| SCHEMBL10228486 | 0.70 | TDP1 (0.35) | TDP1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL12963614 | 0.70 | TDP1 (0.45) | ATMTDP1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL13066991 | 0.68 | TDP1 (0.41) | TDP1SMN1; SMN2KDM4EMAPTHPGD | |
| SCHEMBL1848482 | 0.68 | TSHR (0.42) | ATMTDP1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL23480027 | 0.68 | MEN1 (0.50) | TDP1SMN1; SMN2KDM4EMAPTRAB9A | |
| SCHEMBL24775105 | 0.68 | ALDH1A1 (0.38) | ATMSMN1; SMN2RAB9ALMNAHPGD | |
| SCHEMBL23969741 | 0.68 | AKT1 (0.35) | ATMRAB9ALMNAHPGDALDH1A1 | |
| SCHEMBL1537422 | 0.67 | MAPT (0.40) | ATMTDP1SMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |