Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 2/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969673 | 0.78 | ATM (0.37) | ATMALDH1A1CES2CES1HPGD | |
| SCHEMBL19624772 | 0.77 | AKT1 (0.39) | AKT1ALDH1A1CES2CES1HPGD | |
| SCHEMBL20305986 | 0.70 | MTNR1A (0.38) | ATMALDH1A1CES2CES1HPGD | |
| SCHEMBL12963614 | 0.70 | TDP1 (0.45) | AKT1ATMALDH1A1CES2CES1 | |
| SCHEMBL10228486 | 0.70 | TDP1 (0.35) | ALDH1A1CES2CES1HPGD | |
| SCHEMBL13066991 | 0.68 | TDP1 (0.41) | AKT1ALDH1A1CES2CES1HPGD | |
| SCHEMBL23969709 | 0.68 | ATM (0.35) | ATMALDH1A1HPGDRAB9ALMNA | |
| SCHEMBL23193036 | 0.66 | NFE2L2 (0.38) | AKT1ATMALDH1A1LMNA | |
| SCHEMBL18173259 | 0.66 | LMNA (0.47) | ALDH1A1LMNA | |
| SCHEMBL2875060 | 0.66 | LMNA (0.47) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904366-A1 | END CAPPED NUCLEIC ACID MOLECULES | Novartis AG (CH) | 2021-11-03 | — | — | EP | disclosed |