Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 5/20 | 0.47 |
| ▸ | RXRA | P19793 | 5/20 | 0.45 |
| ▸ | RXRG | P48443 | 5/20 | 0.45 |
| ▸ | RXRB | P28702 | 4/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969869 | 0.87 | ALDH1A1 (0.64) | ALDH1A1PTPN1 | |
| SCHEMBL5429627 | 0.81 | KIF11 (0.57) | ALDH1A1KIF11 | |
| SCHEMBL14418354 | 0.81 | ALDH1A1 (0.73) | ALDH1A1DHODHPTPN1 | |
| SCHEMBL223423 | 0.81 | ALDH1A1 (0.73) | ALDH1A1DHODHPTPN1 | |
| SCHEMBL31093906 | 0.79 | KIF11 (0.65) | ALDH1A1KIF11RXRARXRGRXRB | |
| SCHEMBL14471626 | 0.77 | ALDH1A1 (0.60) | ALDH1A1DHODHPTPN1 | |
| SCHEMBL28222642 | 0.77 | KIF11 (0.70) | ALDH1A1KIF11RXRARXRGRXRB | |
| Nitrogen SCHEMBL27657438 | 0.75 | KIF11 (0.60) | ALDH1A1KIF11RXRARXRGRXRB | |
| SCHEMBL183175 | 0.75 | EPHX2 (0.52) | ALDH1A1KIF11 | |
| SCHEMBL2138447 | 0.75 | KIF11 (0.65) | ALDH1A1KIF11RXRARXRGRXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3353156-B1 | TEAD TRANSCRIPTION FACTOR AUTOPALMITOYLATION INHIBITORS | MASSACHUSETTS GEN HOSPITAL (US) | 2021-11-03 | — | — | EP | disclosed |