Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.65 |
| ▸ | RXRA | P19793 | 3/20 | 0.59 |
| ▸ | RXRB | P28702 | 3/20 | 0.59 |
| ▸ | RXRG | P48443 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28222642 | 0.98 | KIF11 (0.70) | KIF11RXRARXRBRXRGALDH1A1 | |
| Nitrogen SCHEMBL27657438 | 0.95 | KIF11 (0.60) | KIF11RXRARXRBRXRGALDH1A1 | |
| SCHEMBL31093906 | 0.95 | KIF11 (0.65) | KIF11RXRARXRBRXRGALDH1A1 | |
| SCHEMBL5123246 | 0.87 | RXRA (0.58) | KIF11RXRARXRBRXRGALDH1A1 | |
| SCHEMBL25489511 | 0.85 | RXRA (0.48) | KIF11RXRARXRBRXRGALDH1A1 | |
| SCHEMBL15499268 | 0.85 | RXRA (0.48) | KIF11RXRARXRBRXRGALDH1A1 | |
| SCHEMBL4266470 | 0.85 | KIF11 (0.54) | KIF11RXRARXRBRXRGALDH1A1 | |
| SCHEMBL3783746 | 0.85 | KIF11 (0.54) | KIF11RXRARXRBRXRGALDH1A1 | |
| SCHEMBL17204158 | 0.85 | KIF11 (0.54) | KIF11RXRARXRBRXRGALDH1A1 | |
| SCHEMBL30087058 | 0.85 | KIF11 (0.54) | KIF11RXRARXRBRXRGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689394-B2 | Thieno[2,3-b]pyridine derivative, quinoline derivative, and use thereof | THE UNIVERSITY OF TOKYO (JP) | 2020-06-23 | — | — | US | claimed |
| US-20190177336-A1 | THIENO[2,3-b]PYRIDINE DERIVATIVE AND QUINOLINE DERIVATIVE, AND USE THEREOF | THE UNIVERSITY OF TOKYO (JP) | 2019-06-13 | — | — | US | claimed |
| EP-1667958-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-14 | — | — | EP | claimed |
| WO-2005033063-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-14 | — | — | WO | claimed |
| US-20050075324-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-07 | — | — | US | claimed |
| WO-2023148215-A1 | 3,6-BIS(CYANOMETHYLIDENE)CYCLOHEXA-1,4-DIENE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONIC DEVICES | NOVALED GMBH (DE) | 2023-08-10 | — | — | WO | disclosed |
| EP-4223739-A1 | 3,6-BIS(CYANOMETHYLIDENE)CYCLOHEXA-1,4-DIENE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONIC DEVICES | Novaled GmbH (DE) | 2023-08-09 | — | — | EP | disclosed |
| US-11664093-B2 | Extrapolative prediction of enantioselectivity enabled by computer-driven workflow, new molecular representations and machine learning | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-05-30 | — | — | US | disclosed |
| US-11444250-B2 | Composition of matter for use in organic light-emitting diodes | KYULUX, INC. (JP) | 2022-09-13 | — | — | US | disclosed |
| CN-113200938-B | Benzisothiazole hypoxia inducible factor 2 agonist compound or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2022-08-26 | — | — | CN | disclosed |
| CN-114364653-A | Cerium (IV) complexes and their use in organic electronic components | 克雷多西斯有限公司 | 2022-04-15 | — | — | CN | disclosed |
| US-11179710-B2 | Direct palladium-catalyzed aromatic fluorination | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-23 | — | — | US | disclosed |
| WO-2005033063-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-14 | — | — | WO | disclosed |
| US-6878830-B2 | Catalytic boronate ester synthesis from boron reagents and hydrocarbons | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2005-04-12 | — | — | US | disclosed |
| US-20050075324-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-07 | — | — | US | disclosed |
| US-6867302-B2 | Process for the catalytic synthesis of biaryls and polymers from aryl compounds | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2005-03-15 | — | — | US | disclosed |
| EP-1473286-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-20030109380-A1 | Catalytic boronate ester synthesis from boron reagents and hydrocarbons | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 2003-06-12 | — | — | US | disclosed |
| US-20030109713-A1 | Process for the catalytic synthesis of biaryls and polymers from aryl compounds | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2003-06-12 | — | — | US | disclosed |
| US-6255545-B1 | BROMINATION OF BENZENE, M-BIS/TRIFLUOROMETHYL/-WITH 1,3-DIBROMO-5,5-DIMETHYLHYDANTOIN OR BROMOSUCCINIMIDE IN THE PRESENCE OF ACETIC ACID AND SULFURIC ACID | MERCK & CO., INC. | 2001-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689394-B2 | Thieno[2,3-b]pyridine derivative, quinoline derivative, and use thereof | BRD4, DRD4, TH | KIF11 3418/4885RXRA 1101/4885RXRB 729/4885 |
| US-20050075324-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC1R | KIF11 4169/4885RXRA 1395/4885RXRB 1565/4885 |
| US-11444250-B2 | Composition of matter for use in organic light-emitting diodes | CRY2, ALDH1A2, CYBA | KIF11 3284/4885RXRA 1400/4885RXRB 1086/4885 |
| US-11179710-B2 | Direct palladium-catalyzed aromatic fluorination | KRAS, NRAS, DDT | KIF11 414/4885RXRA 566/4885RXRB 576/4885 |
| US-20030109713-A1 | Process for the catalytic synthesis of biaryls and polymers from aryl compounds | PAH, BRSK1, BLVRB | KIF11 4395/4885RXRA 3363/4885RXRB 2428/4885 |
| US-20190177336-A1 | THIENO[2,3-b]PYRIDINE DERIVATIVE AND QUINOLINE DERIVATIVE, AND USE THEREOF | DERL1, UBQLN1, ADRM1 | KIF11 2686/4885RXRA 3110/4885RXRB 2852/4885 |
| US-20030109380-A1 | Catalytic boronate ester synthesis from boron reagents and hydrocarbons | HBB, BTD, HMBS | KIF11 4621/4885RXRA 438/4885RXRB 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.