Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969872 | 0.81 | NPC1 (0.39) | LMNAMAPTNPC1EPHX2ALDH1A1 | |
| SCHEMBL25720525 | 0.79 | MEN1 (0.39) | LMNAMAPTNPC1EPHX2ALDH1A1 | |
| SCHEMBL22815627 | 0.79 | MAPT (0.40) | LMNAMAPTNPC1EPHX2ALDH1A1 | |
| SCHEMBL17347046 | 0.77 | LMNA (0.63) | LMNAMAPTNPC1EPHX2ALDH1A1 | |
| SCHEMBL26017002 | 0.75 | MEN1 (0.36) | LMNANPC1ALDH1A1GFERMEN1 | |
| SCHEMBL19647750 | 0.72 | ALDH1A1 (0.47) | LMNAMAPTNPC1ALDH1A1GFER | |
| SCHEMBL26739637 | 0.72 | ALDH1A1 (0.40) | LMNAMAPTALDH1A1GFERRECQL | |
| SCHEMBL25872113 | 0.72 | PDK2 (0.38) | LMNAMAPTNPC1EPHX2 | |
| SCHEMBL22453675 | 0.71 | NPC1 (0.32) | NPC1 | |
| SCHEMBL22453131 | 0.70 | ALDH1A1 (0.40) | LMNAMAPTNPC1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3353156-B1 | TEAD TRANSCRIPTION FACTOR AUTOPALMITOYLATION INHIBITORS | MASSACHUSETTS GEN HOSPITAL (US) | 2021-11-03 | — | — | EP | disclosed |