Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26137719 | 0.86 | PARP1 (0.32) | PARP1 | |
| SCHEMBL18368373 | 0.82 | GCGR (0.31) | — | |
| SCHEMBL14349193 | 0.81 | KDM4E (0.46) | — | |
| SCHEMBL20665898 | 0.79 | TRPA1 (0.32) | PARP1ELANE | |
| SCHEMBL27342258 | 0.79 | — | — | |
| SCHEMBL22868493 | 0.78 | LMNA (0.34) | — | |
| SCHEMBL19301851 | 0.78 | GABRA1 (0.35) | — | |
| SCHEMBL27347836 | 0.78 | GCGR (0.31) | PARP1 | |
| SCHEMBL16387005 | 0.75 | PDCD1LG2 (0.35) | ELANE | |
| SCHEMBL23565850 | 0.75 | CRHR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222353-A1 | MACROCYCLIC INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |