Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | F9 | P00740 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR5A | P47898 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17640479 | 0.78 | LIMK1 (0.45) | LIMK1PDE3BPDE3AROCK1HTR2B | |
| SCHEMBL17640482 | 0.77 | LIMK1 (0.47) | LIMK1PDE3BPDE3AROCK1F9 | |
| SCHEMBL23972156 | 0.77 | KDM4E (0.40) | LIMK1PDE3BPDE3AHTR2BHTR5A | |
| SCHEMBL22880101 | 0.75 | L3MBTL1 (0.41) | F9ESR1ESR2PIK3CAPI4KA | |
| SCHEMBL13245724 | 0.75 | LIMK1 (0.45) | LIMK1PDE3BPDE3AROCK1HTR2B | |
| SCHEMBL28191720 | 0.75 | MAP4K4 (0.47) | PDE3BPDE3AHTR2BHTR5ATDO2 | |
| SCHEMBL19080227 | 0.75 | CYP1A1 (0.45) | LIMK1F9ESR1ESR2 | |
| SCHEMBL16922468 | 0.73 | LIMK1 (0.38) | LIMK1PDE3BPDE3AROCK1HTR2B | |
| SCHEMBL20149676 | 0.73 | PDE3B (0.43) | LIMK1PDE3BPDE3AHTR2BHTR5A | |
| SCHEMBL11941207 | 0.73 | HTR2B (0.44) | LIMK1PDE3BPDE3AROCK1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210343950-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORP (US) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210343950-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | AOX1, OCIAD1, OCIAD2 | LIMK1 3475/4885PDE3B 3066/4885PDE3A 3940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.