SCHEMBL23972186

SCHEMBL23972186

c1ccc(-c2nc(-c3cccc(-c4cccc(-c5nc(-n6c7ccccc7c7cc(-c8ccc9c(c8)c8ccccc8n9-c8ccccc8)ccc76)nc6ccccc56)c4)c3)nc(-n3c4ccccc4c4ccc5c6ccccc6sc5c43)n2)cc1

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
PTGER4 P35408 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21965503 0.92 KMT2A (0.38) MEN1KMT2AATMKDM4EALDH1A1
SCHEMBL18542842 0.92 PTGER4 (0.32) MEN1KMT2AATMPTGER4KDM4E
SCHEMBL8815486 0.92 ALDH1A1 (0.37) MEN1KMT2AATMPTGER4KDM4E
SCHEMBL15138846 0.88 PTGER4 (0.34) ATMPTGER4KDM4EMAPTL3MBTL1
SCHEMBL17246753 0.87 KDM4E (0.35) ATMPTGER4KDM4EL3MBTL1
SCHEMBL21965518 0.87 TNKS (0.32) PTGER4MAPT
SCHEMBL21965526 0.87 TNKS (0.32) PTGER4MAPT
SCHEMBL15582481 0.86 KDM4E (0.33) ATMPTGER4KDM4EALDH1A1MAPT
SCHEMBL16785810 0.86 ALOX5 (0.40) ATMPTGER4KDM4EALDH1A1MAPT
SCHEMBL8815497 0.86 ATM (0.40) MEN1KMT2AATMPTGER4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11765966-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
US-20220359836-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-11-10 US disclosed
US-20210343950-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2021-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210343950-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AOX1, OCIAD1, OCIAD2 MEN1 4654/4885KMT2A 1952/4885ATM 4078/4885
US-20220359836-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, EPM2A MEN1 1877/4885KMT2A 3949/4885ATM 3147/4885
US-11765966-B2 Organic electroluminescent materials and devices L1CAM, EPCAM, EPM2A MEN1 1877/4885KMT2A 3949/4885ATM 3147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.